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KMID : 0359720070250020247
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Journal of the Korean Neurological Association
2007 Volume.25 No. 2 p.247 ~ p.250
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A Case of Essential Cryoglobulinemic Neuropathy
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Lee Sang-Soo
Song Myung-Ja
Han Ho-Seong
Shin Dong-Ick
Lee Sung-Hyun
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Abstract
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Mixed cryoglobulinemia occurs predominantly in association with chronic liver disease, infections, autoimmune diseases, and malignancies. Mixed cryoglobulinemia is classified as essential if no primary disease is identified. We report a 42-year-old woman with a painful essential cryoglobulinemic neuropathy. She developed arthralgia, purpura, and subacute multifocal sensorimotor neuropathy. Laboratory studies did not show any associated conditions except for an elevated cryoglobulin level. An electrophysiological study and nerve biopsy were indicative of multifocal axonal neuropathy. The neuropathy was stabilized with immunosuppressive treatment.
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KEYWORD
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Cryoglobulinemia, Vasculitic neuropathy, Mononeuritis multiplex
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